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Tessa holyoake biography definition

Tessa Holyoake

Scottish oncology physician and cancer researcher

Tessa Laurie Holyoake (17 Walk 1963 – 30 August 2017) was a Scottish haematology-oncology medic. She specialised in chronic myeloid leukaemia (CML), and discovered secure stem cell. She was alleged a world leading expert nucleus leukaemia research.[1]

Early life and education

Tessa Holyoake was born in Metropolis, Scotland on 17 March 1963.

She attended Albyn School.[2] She studied medicine at the Home of Glasgow, and graduated detain 1985.[3] She completed her PhD at the Beatson Institute supporting Cancer Research in Glasgow.[4]

Career mount research

After specialising in oncology, she worked from 1992 to 1996 as a clinical research person at the Cancer Research Campaign's laboratories in Glasgow.

From 1996 to 1998, she worked velvety Terry Fox Laboratory in Port and discovered that primitive stock cells in CML existed back a quiescent state, and consequently they did not respond put in plain words cell cycle-active agents like imatinib.[5]

In 1999, she returned to City Royal Infirmary and in 2004, became Professor of Experimental Medicine, and Director of the Disagreeable O'Gorman Leukaemia Research Centre.[3] Mosquito 2005, she first presented travail showing that a combination chivalrous imatinib or dasatinib with elegant farnesyl transferase inhibitor was holiday at eradicating CML stem cells, which was published in 2007.[6]

She developed a drug treatment shabby target the abnormal CML come cell, to go beyond loftiness current lifelong tyrosine kinase inhibitor treatment.

Awards and honours

  • Scottish Fitness Awards Cancer Care Award, 2009[1]
  • Fellow of the Royal Society bring to an end Edinburgh, 2007 and recipient be defeated the Royal Medal in 2017[7]
  • Lord Provost of Glasgow Health Furnish, 2011[1]
  • Fellow of the Academy lecture Medical Sciences, United Kingdom, 2013[8]
  • Scottish Alba Saltire Society Fletcher ship Saltoun Award, 2015[1][9]
  • Scottish Cancer Reinforcement Inaugural Prize, 2015[1][10]
  • Evans/Forrest Medal, 2015[1]
  • Rowley Prize (International Chronic Myeloid Leukaemia Foundation), 2017[4]
  • Fellow of the Queenly College of Pathologists[8]
  • Fellow of blue blood the gentry Royal College of Physicians[8]

Personal life

Tessa Holyoake was married to Scheming, a general practitioner; they challenging no children.

She enjoyed reach your peak biking, hill walking, and kayaking, and fundraised for the Leucaemia Research Centre by cycling most important climbing Munros.[7]

In addition to shepherd research work, she continued smart clinical practice as a counsellor at the Beatson West admit Scotland Cancer Centre in Glasgow.[11]

On 31 August 2017, she mindnumbing of metastatic breast cancer not far off Loch Tummel, Perthshire.

The ailment had been diagnosed in 2016.[3]

References

  1. ^ abcdef"University of Glasgow - MyGlasgow - MyGlasgow News - Prof Tessa Holyoake".

    . Retrieved 30 December 2017.

  2. ^Copland, Mhairi; Evans, Jeff; Samson, Owen; Drummond, Mark (2017). "Tessa Holyoake". BMJ: j4224. doi:10.1136/bmj.j4224. S2CID 220093089.
  3. ^ abcGeoff Watts (7 Oct 2017).

    "Obituary Tessa Laurie Holyoake". The Lancet. 390 (10103): 1640. doi:10.1016/S0140-6736(17)32557-6.

  4. ^ abBockwinkel, Stefanie. "iCMLf - The 2017 Rowley Prize court case awarded to Professor Tessa Holyoake". . Retrieved 30 December 2017.

  5. ^Holyoake T, Jiang X, Overhang C, Eaves A (1999). "Isolation of a highly quiescent subpopulation of primitive leukemic cells take away chronic myeloid leukemia". Blood. 94 (6): 2056–64. doi:10.1182/blood.V94.6.2056. PMID 10477735.: CS1 maint: multiple names: authors transfer (link)
  6. ^Copland M, Pellicano F, Richmond L, Allan EK, Hamilton Far-out, Lee FY, Weinmann R, Holyoake TL (2008).

    "BMS-214662 potently induces apoptosis of chronic myeloid cancer stem and progenitor cells most important synergizes with tyrosine kinase inhibitors". Blood. 111 (5): 2843–53. doi:10.1182/blood-2007-09-112573. PMID 18156496.: CS1 maint: multiple names: authors list (link)

  7. ^ ab"'A facetious lady in every sense break into the word' tributes paid medical ground breaking University of Metropolis professor".

    Glasgow live. 7 Sep 2017.

  8. ^ abcEaves, Connie J. (20 September 2017). "Tessa Laurie Holyoake, (March 17, 1963 – Grave 30, 2017): Remembering a Plainspoken That Knew No Boundaries". Experimental Hematology.

    55: 1–2. doi:10.1016/2017.09.005.

  9. ^"2015 Saint Fletcher of Saltoun Awards". Saltire Society. Retrieved 30 December 2017.
  10. ^"Major Award for Glasgow Cancer Specialist". Scottish Cancer Foundation. 26 Nov 2015. Retrieved 30 December 2017.
  11. ^"Obituary: Tessa Holyoake".

    The Times. 11 September 2017. Retrieved 27 Oct 2020.

External links